Programme Day 1

9.00 – 10.30

Hall: King Willem-Alexander

Education session in collaboration with Dutch Society of  Thrombosis and Haemostasis (NVTH)

How to be a good scientist

 

How to be a good scientist

  • Innovations in Scholarly Communication, Bianca Kramer and Jeroen Bosman, The Netherlands
  • The dos and don’ts of writing European grants, Doenja Koppejan, The Netherlands

10.30 – 11.00

Foyer

Coffee Break & Poster Viewing

11.00 – 12.00

Hall: King Willem-Alexander

Education session in collaboration with Dutch Society of  Thrombosis and Haemostasis (NVTH)

Science with a broad view

Science with a broad view

  • It takes two to tango: Net formation and haemolysis, Sacha Zeerleder, The Netherlands
  • The polyphosphate tail: a primitive biomolecule with haemostatic function, Nicola Mutch, United Kingdom

12.00 – 13.00

Foyer

PhD Network & Career Lunch

The first day of ECTH features the PhD Network & Career lunch. This is a great chance for young doctoral candidates to meet with representatives from industry and (research) organisations linked to thrombosis and heamostatis.

Students can establish contact in a relaxed atmosphere and get to know the various companies as well as potential employers.

13.00 – 14.30

Oral communications

Clotting – Venous thrombosis

Hall: King Willem-Alexander

Oral communications
Clotting – Venous thrombosis

  • Sex-specific differences in prevalence of pulmonary embolism among patients with venous thromboembolism, Luuk Scheres, The Netherlands
  • The risk of recurrent venous thrombosis in patients undergoing surgery after a first thrombotic event, Banne Nemeth, The Netherlands
  • Association of impaired renal function with venous thrombosis: a genetic risk score approach, Romain Charmet, France
  • Repeated measures of carotid atherosclerosis and future risk of venous thrombosis, Birgit Småbrekke, Norway
  • Protein C activity is associated to early formation of new Q waves and failure to achieve ST segment resolution in patients with acute ST segment elevation myocardial infarction, Slobodan Obradovic, Serbia
  • PDGFB, a new candidate plasma biomarker for venous thromboembolism, Maria Jesus Iglesias, Sweden

Oral communications

Clotting – Structure and function

Hall: Amazon

Oral communications
Clotting – Structure and function

  • Tissue factor expressed by different cell types regulates central nervous system haemostasis and autoimmune inflammation in a mouse model of multiple sclerosis, Rafal Pawlinski, United States
  • The C-terminus of TFPIα inhibits factor V activation by protecting the Arg1545 cleavage site, Peter van Doorn, The Netherlands
  • Factor V functions as a synergistic cofactor with protein S in the inhibition of FXa by TFPI, Salvatore Santamaria, United Kingdom
  • New modulators of SERPINC1 gene expression. Relevance for antithrombin levels and potential therapeutic usefulness, Mara Toderici, Spain
  • Conformational activation of ADAMTS13: The spacer-CUB/VWF-D4CK domain interactions, Kieron South, United Kingdom

Oral communications

Bleeding – Experimental models

Hall: Mississippi

Oral communications
Bleeding – Experimental models

  • Complete loss of CalDAG-GEFI expression leads to severe bleedings caused by altered platelet function, Matthias Canault, France
  • A fusion protein of interleukin-4 and interleukin-10 protects against blood-induced cartilage damage in vitro and in vivo, Lize van Vulpen, The Netherlands
  • Matrix metalloproteinase inhibition (CM352) effectively reduces rivaroxaban but not dabigatran associated experimental bleeding, Jose A. Paramo, Spain
  • Efficient and allele-specific siRNAs that target von Willebrand factor single nucleotide polymorphisms as a potential personalized therapy for von Willebrand disease, Annika de Jong, The Netherlands
  • The  correlation between biomarkers of joint cartilage degradation and markers of oxidative stress in patients with severe haemophilia treated by different prophylaxis regimens, Mirjana Mitrovic, Serbia
  • Depletion of prekallikrein improves host defense  during Gram-negative pneumonia derived sepsis, Chao Ding, The Netherlands

Oral communications

Platelets – Mechanisms and regulation

Hall: Yangtze 1&2

Oral communications
Platelets – Mechanisms and regulation

  • GPV is a central regulator of haemostasis, thrombosis and thrombo-inflammatory brain infarction in mice, Sarah Beck, Germany
  • Blocking heteromerization of platelet chemokines CCL5 and CXCL4 reduces inflammation and preserves heart function after myocardial infarction, Rory Koenen, The Netherlands
  • Platelet-derived S1P promotes recovery from anaphylactic shock but is redundant for vascular integrity, Eric Camerer, France
  • Defects in TRPM7 function result in abnormal Ca2+ dependent platelet signaling in mice, Sanjeev Gotru, Germany
  • Platelet-thrombi induce an unstable plaque phenotype and arterial stiffening locally at the site of vascular injury, Judith Cosemans, The Netherlands
  • Platelet function testing in patients with cerebral aneurysms treated with endovascular procedures and dual antiplatelet therapy, Rosa Vidal, Spain

 

14.30 – 15.00

Foyer

Coffee Break & Poster Viewing

15.00 – 16.00

Hall: King Willem-Alexander

16.00 – 17.00

Hall: King Willem-Alexander

Science, fast and furious

Guided ‘TEDx-style’ science-showcases in a fast and furious session with the latest insights from international experts

Science, fast and furious

  • Characterization of two novel RASGRP2 variants leading to defective CalDAG-GEFI- mediated RAP1 activation and platelet dysfunction, Maria Luisa Lozano, Spain
  • Light sheet fluorescence microscopy (LSFM) and subsequent quantitative structural analysis of megakaryocytes in intact murine bone, Mari Gorelashvili, Germany
  • Modeling the risk of recurrent venous thrombosis – Where are we now and what can we add, Jasmijn Timp, The Netherlands
  • Thrombotic activity in the acutely ischaemic brain is dramatically reduced in T-cell deficient mice, David Stegner, Germany

17.00 – 17.45

Hall: King Willem-Alexander

Opening Ceremony

We invite all delegates of the ECTH 2016 to the official Opening Ceremony. You will be treated to a dynamic spectacle of music by the Royal Conservatoire and welcomed by Saskia Middeldorp (Host ECTH 2016 and president NVTH) and Frits Rosendaal (Board ECTH 2016).

The keynote lecture will reflect on ways to increase synergy across Europe to improve the chances of funding and the relevance of research. We look forward to seeing you there.

17.45 – 19.00

Foyer

Welcome Reception

After an entertaining Opening Ceremony, chat and mingle with fellow congress visitors and enjoy a drink along with some delicious bites. Welcome to The Hague!