Programme Day 3

9.00 – 10.00

Oral communications

Platelets – Clinical aspects

Hall: King Willem-Alexander

Oral communications
Platelets – Clinical aspects

  • Stefin A, a novel megakaryocyte and platelet protein regulated by the metabolic status, Anna Mezzapesa, France
  • ADAMTS13 containing the naturally occurring mutation p.arg1177gln adopts an open conformation, Elien Roose, Belgium
  • Age-related increase of thromboxane B2 and risk of cardiovascular disease in atrial fibrillation, Pasquale Pignatelli, Italy
  • Haemostatic abnormalities in patients with Ehlers-Danlos syndrome, Andrea Artoni, Italy

Oral communications

Clotting – Thrombus formation

Hall: Amazon

Oral communications
Clotting – Thrombus formation

  • Inhibition of TAFI and PAI-1 reduces ischaemic stroke brain damage, Frederik Denorme, Belgium
  • Low haematocrit thrombi form more rapidly and are more resistance to fibrinolytic degradation as a result of increased cross-linking by factor XIIIa, Paraskevi Untiveros, United Kingdom
  • Development of a method for in vivo detection of active thrombi in mice, Annemiek Dickhout, The Netherlands
  • Granulocyte clone size and eculizumab impact clot structure in patients with paroxysmal nocturnal haemoglobinuria, Polly Bowman, United Kingdom

Oral communications

Bleeding – Haemophilia

Hall: Mississippi

Oral communications
Bleeding – Haemophilia

  • Efficacy and safety of recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in previously treated adult and adolescent patients with haemophilia B, Alex Veldman, Germany
  • Variation in baseline factor VIII concentration in mild and moderate hemophilia A patients carrying the same F8 mutation, Janneke Loomans, The Netherlands
  • Non-neutralizing antibodies against factor VIII and the risk of inhibitor development in patients with severe haemophilia, Antonino Cannavo, Italy
  • Next-generation sequencing for haemophilia A and B genotyping in Lille university hospital, Fanny Lassalle, France

10.00 – 10.30

Foyer

Coffee

10.30 – 11.30

Hall: King Willem-Alexander

State of the Art

 

Modulation of alternative splicing of coagulation genes: a new approach to prevent venous thrombosis

Elisabetta Castoldi

State of the Art

 

Key points in the diagnosis and treatment of venous thromboemolism

Cecilia Beccattini

10.30 – 11.30

Hall: Amazon

State of the Art

 

Advancing therapeutics in haemophilia

Peter Collins

11.45 – 12.45

Hall: King Willem-Alexander

Science, fast and furious

Guided ‘TEDx-style’ science-showcases in a fast and furious session with latest insights from international experts

Science, fast and furious

  • Platelet polyphosphate forms solid nanoparticles that are exposed on the cell surface and can trigger contact system activation, Johan Verhoef, The Netherlands
  • The association of circulating DNA, nucleosomes, and neutrophil extracellular traps with the severity and outcome of venous thromboembolism in patients, Miguel Jiménez-Alcázar, Germany
  • Characteristics and treatment of vaginal bleeding in women with venous thromboembolism treated with apixaban or enoxaparin followed by warfarin, Marjolein Brekelmans, The Netherlands
  • Neutrophil extracellular traps in thrombi from patients with acute ischaemic stroke, Elodie Laridan, Belgium

12.45 – 13.45

Foyer

Lunch

13.45 – 14.30

Hall: King Willem-Alexander

14.30 – 15.00

Hall: King Willem-Alexander

Closing